Two sample MR report
RRP7A_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 14 | -0.0367516 | 0.1940979 | 0.8529866 |
| Weighted median | 14 | -0.0883418 | 0.0197828 | 0.0000080 |
| Inverse variance weighted | 14 | -0.0653068 | 0.0189405 | 0.0005647 |
| Simple mode | 14 | -0.0901931 | 0.0272365 | 0.0056222 |
| Weighted mode | 14 | -0.0896037 | 0.0264276 | 0.0048294 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 22.85366 | 12 | 0.0289943 |
| Inverse variance weighted | 22.89531 | 13 | 0.0429499 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0218947 | 0.1480563 | 0.8848927 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003062 | 0 | TRUE | 0.0978363 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
